Blood Rune
Inflicts a bleed effect on enemies, dealing damage over 5 seconds. Blood Rune scales from 65% bleed damage at base to 97% at max level. Longer duration than Inferno Rune but slightly lower total damage.
Bonus & Scaling
| Property | Value |
|---|---|
| Bonus Type | Bleed DoT Damage |
| Scaling | Base: 65% total DMG over 5s → Max (Lv50): 97% total DMG over 5s |
| Location | Rune Dungeon — rare drop |
| Cost (Fragments) | Free (drop) |
Base: 65% total DMG over 5s → Max (Lv50): 97% total DMG over 5s
How to Get Blood Rune
Rune Dungeon — rare drop
Rune Dungeon
Access the Rune Dungeon using a Dungeon Key. Clear all 15 waves for a chance at rune drops.
Drop Rate
Rare drop from the Rune Dungeon. Higher-tier runes have lower drop rates.
Rune Leveling
Max Level
Lv50
Duplicates Needed
502
Equip Limit
1 Rune
Runes are leveled by feeding duplicate copies. Each level increases the rune's bonus. Only one rune can be equipped at a time, so choose wisely.
Usage Tips
- Damage runes are the most versatile choice, boosting all damage output universally.
- Pairs well with high-DPS fruits and swords for maximum burst damage.
- DoT (Damage over Time) runes provide sustained damage, great for extended boss fights.
- Less effective in PvP where burst damage is preferred over sustained damage.
- Only one rune can be equipped at a time. Prioritize leveling your primary rune to Lv50 before investing in others.
Used in Builds
Blood Rune synergizes with 4 builds.
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At a Glance
Quick Overview
Blood Rune
B TierBonus
Bleed DoT Damage
Location
Rune Dungeon — rare
Inflicts a bleed effect on enemies, dealing damage over 5 seconds. Blood Rune sc...
Tier Position
Ranked #8 of 11 in Runes
Blood Rune is in B Tier
Synergy Recommendations
Best Pairings & Synergies
Best Fruits to Pair
Related Content
All Runes Database
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View Blood Rune on Runes Tier List
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Best Builds with Blood Rune
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Active Codes
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Build Optimizer
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Accessories Wiki
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Blood Rune — Info
- Tier
- B
- Bonus Type
- Bleed DoT Damage
- Scaling
- Base: 65% total DMG over 5s → Max (Lv50): 97% total DMG over 5s
- Location
- Rune Dungeon
- Cost
- Free (drop)
- Max Level
- Lv50
- Last Updated
- 2026-03-15